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用再生疗法逆转听力损失

Most of us know someone affected by hearing loss, but we may not fully appreciate the hardships that lack of hearing can bring. Hearing loss can lead to isolation, frustration, and a debilitating ringing in the ears known as tinnitus. It is also closely correlated with dementia. The biotechnology company Frequency Therapeutics is seeking to reverse hearing loss — not with hearing aids or implants, but with a new kind of regenerative therapy. The company uses small molecules to program progenitor cells, a descendant of stem cells in the inner ear, to create the tiny hair cells that allow us to hear.

Apr 8, 2022

什么是干细胞移植?

干细胞移植是指将健康的干细胞注入人体的骨髓或血液中。当一个人的骨髓因化疗、放疗或疾病而受损时,这可以补充干细胞。当健康细胞来自骨髓时,也称为骨髓移植。

Apr 6, 2022

干细胞治疗可能治愈了女性的 HIV

一名艾滋病毒呈阳性的妇女接受了造血干细胞移植来治疗急性髓系白血病,艾滋病毒似乎已被治愈。这些来自脐带血的干细胞含有一种基因变异,使它们能够抵抗艾滋病毒感染。自接受治疗以来,该妇女已不再感染艾滋病毒 14 个月。这一发现可能为某些患者的艾滋病毒治疗指明方向。一名中年、混血、艾滋病毒呈阳性的女性自从因另一种情况接受造血干细胞移植后已经摆脱了病毒。

Apr 6, 2022

发现糖衣 RNA 分子开辟了细胞生物学的新领域

我们体内的细胞充满了被称为聚糖的糖,其他细胞可以通过专门的受体识别这些糖。通过附着和修饰蛋白质和脂肪,聚糖会影响蛋白质的折叠方式、信号在细胞之间的传递方式以及其他细胞与细胞之间的相互作用。作为聚糖重要性的一个例子,我们的血型(A、B、O)取决于红细胞将哪些糖纳入其保护层。

Aug 9, 2021

“振兴”阿尔茨海默氏症的大脑

Alzheimer’s disease is the main cause of dementia and current therapeutic strategies cannot prevent, slow down or cure the pathology. The disease is characterized by memory loss, caused by the degeneration and death of n…

Aug 5, 2021

“振兴”阿尔茨海默氏症的大脑

Alzheimer's disease is the main cause of dementia and current therapeutic strategies cannot prevent, slow down or cure the pathology. The disease is characterized by memory loss, caused by the degeneration and death of neuronal cells in several regions of the brain, including the hippocampus. Researchers have identified a small molecule that can be used to rejuvenate the brain and counteract the memory loss.

Aug 5, 2021

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