{"id":86,"date":"2021-05-05T16:13:00","date_gmt":"2021-05-05T14:13:00","guid":{"rendered":"http:\/\/blog.cell-lavie.com\/?p=86"},"modified":"2022-11-01T05:06:53","modified_gmt":"2022-11-01T05:06:53","slug":"non-neutralizing-secretory-iga-and-t-cells-targeting-sars-cov-2-spike-protein-are-transferred-to-the-breastmilk-upon-bnt162b2-vaccination","status":"publish","type":"post","link":"https:\/\/cell-lavie.com\/zh\/non-neutralizing-secretory-iga-and-t-cells-targeting-sars-cov-2-spike-protein-are-transferred-to-the-breastmilk-upon-bnt162b2-vaccination\/","title":{"rendered":"\u5728 BNT162b2 \u75ab\u82d7\u63a5\u79cd\u540e\uff0c\u9776\u5411 SARS-CoV-2 \u523a\u7a81\u86cb\u767d\u7684\u975e\u4e2d\u548c\u6027\u5206\u6ccc\u578b IgA \u548c T \u7ec6\u80de\u88ab\u8f6c\u79fb\u5230\u6bcd\u4e73\u4e2d"},"content":{"rendered":"<p>\u9274\u4e8e\u7f3a\u4e4f\u6307\u5bfc\u6bcd\u4e73\u5582\u517b\u5987\u5973\u51b3\u7b56\u7684\u6570\u636e\uff0c\u6211\u4eec\u8bc4\u4f30\u4e86 mRNA \u75ab\u82d7\u5982\u4f55\u5f71\u54cd\u54fa\u4e73\u671f\u533b\u62a4\u4eba\u5458 (HCW) \u7684\u514d\u75ab\u53cd\u5e94\u4ee5\u53ca\u6bcd\u4e73\u8f6c\u79fb\u514d\u75ab\u4fdd\u62a4\u7684\u6548\u5e94\u6982\u51b5\u3002<\/p>\n\n\n<!--more-->\n\n\n<p>\u6211\u4eec\u8868\u660e\uff0c\u5728 BNT162b2 \u75ab\u82d7\u63a5\u79cd\u540e\uff0c\u901a\u8fc7\u5206\u6ccc\u578b IgA (SIgA) \u548c T \u7ec6\u80de\u901a\u8fc7\u4e73\u6c41\u5411\u54fa\u4e73\u5a74\u513f\u8fdb\u884c\u514d\u75ab\u8f6c\u79fb\u3002\u5728\u529f\u80fd\u4e0a\uff0c\u523a\u7a81-SIgA \u662f\u975e\u4e2d\u548c\u7684\uff0c\u5176\u6ef4\u5ea6\u4e0d\u53d7\u75ab\u82d7\u52a0\u5f3a\u514d\u75ab\u7684\u5f71\u54cd\uff0c\u8868\u660e\u523a\u7a81-SIgA \u662f\u7531\u4e73\u817a\u4ee5\u4e0d\u4f9d\u8d56\u4e8e T \u7ec6\u80de\u7684\u65b9\u5f0f\u4ea7\u751f\u7684\u3002\u5c3d\u7ba1\u5979\u4eec\u7684\u4e73\u6c41\u4e2d\u4e0d\u542b\u4e2d\u548c\u6297\u4f53\uff0c\u4f46\u6211\u4eec\u53d1\u73b0\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0c\u54fa\u4e73\u671f\u5987\u5973\u5177\u6709\u66f4\u9ad8\u9891\u7387\u7684 RBD \u53cd\u5e94\u6027\u5faa\u73af\u8bb0\u5fc6 B \u7ec6\u80de\u548c\u66f4\u591a\u7684 RBD-IgG \u6297\u4f53\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u54fa\u4e73\u671f\u548c\u975e\u54fa\u4e73\u671f HCW \u7684\u8840\u6db2\u4e2d\u548c\u6ef4\u5ea6\u76f8\u4f3c\u3002\u9700\u8981\u8fdb\u4e00\u6b65\u7684\u7814\u7a76\u6765\u786e\u5b9a\u8f6c\u79fb\u7684\u6297\u4f53\u548c\u523a\u7a81-T \u7ec6\u80de\u7684\u5b8c\u6574\u529f\u80fd\u6982\u51b5\uff0c\u4ee5\u53ca\u5b83\u4eec\u662f\u5426\u53ef\u4ee5\u4ecb\u5bfc\u54fa\u4e73\u671f\u5a74\u513f\u7684\u4fdd\u62a4\u4f5c\u7528\u3002<\/p>\n\n\n<p>\u8d44\u6e90\uff1a <a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2021.05.03.21256416v1.full.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.medrxiv.org\/content\/10.1101\/2021.05.03.21256416v1.full.pdf<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>\u9274\u4e8e\u7f3a\u4e4f\u6307\u5bfc\u6bcd\u4e73\u5582\u517b\u5987\u5973\u51b3\u7b56\u7684\u6570\u636e\uff0c\u6211\u4eec\u8bc4\u4f30\u4e86 mRNA \u75ab\u82d7\u5982\u4f55\u5f71\u54cd\u54fa\u4e73\u671f\u533b\u62a4\u4eba\u5458 (HCW) \u7684\u514d\u75ab\u53cd\u5e94\u4ee5\u53ca\u6bcd\u4e73\u8f6c\u79fb\u514d\u75ab\u4fdd\u62a4\u7684\u6548\u5e94\u6982\u51b5\u3002<\/p>","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_sitemap_exclude":false,"_sitemap_priority":"","_sitemap_frequency":"","footnotes":""},"categories":[70,72],"tags":[90],"class_list":["post-86","post","type-post","status-publish","format-standard","hentry","category-blog","category-covid-19","tag-covid-19"],"featured_image_src":{"landsacpe":false,"list":false,"medium":false,"full":false},"_links":{"self":[{"href":"https:\/\/cell-lavie.com\/zh\/wp-json\/wp\/v2\/posts\/86","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cell-lavie.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cell-lavie.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cell-lavie.com\/zh\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/cell-lavie.com\/zh\/wp-json\/wp\/v2\/comments?post=86"}],"version-history":[{"count":1,"href":"https:\/\/cell-lavie.com\/zh\/wp-json\/wp\/v2\/posts\/86\/revisions"}],"predecessor-version":[{"id":640,"href":"https:\/\/cell-lavie.com\/zh\/wp-json\/wp\/v2\/posts\/86\/revisions\/640"}],"wp:attachment":[{"href":"https:\/\/cell-lavie.com\/zh\/wp-json\/wp\/v2\/media?parent=86"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cell-lavie.com\/zh\/wp-json\/wp\/v2\/categories?post=86"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cell-lavie.com\/zh\/wp-json\/wp\/v2\/tags?post=86"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}