Intravenous UC-MSCs for Ischemic Stroke: What the MERIT Phase 1 Trial Tells Us

The MERIT phase 1 trial published in Cell Reports Medicine shows that intravenous UC-MSC therapy is safe in subacute ischemic stroke, with early NIHSS improvement signals. Here’s what clinicians need to know.

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MSC Therapy for Graft-versus-Host Disease: What 15 RCTs and a Biomarker-Guided Trial Tell Us

A 2026 meta-analysis of 15 RCTs shows MSCs cut acute GvHD incidence by 53% and chronic GvHD by 50%. A biomarker-guided trial identifies which transplant patients benefit most — and a cell-free exosome approach may be next.

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What is Adaptive Immunity?

Adaptive immunity, also known as acquired immunity or specific immunity, is a subsystem of the overall immune system that provides a tailored defense against specific pathogens. Unlike the innate immune system which offers broad protection, the adaptive immune system is highly specialized to fight each particular pathogen the body encounters.

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