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Pediatric Applications of Stem Cell Therapy

Stem cell therapy holds immense promise for treating rare diseases in children, offering hope for conditions that are often difficult to manage with conventional treatments. Mesenchymal stem cells (MSCs) are particularly…

Jun 2, 2025

Stem Cells in 2024: From Lab to Clinic

Stem cell research in 2024 has seen remarkable progress, with several studies translating lab discoveries into potential clinical applications. This article explores how these advancements are moving from the research be…

Jan 8, 2025

The Role of Microbiome in Immunotherapy for Cancer

Immunotherapy has revolutionized cancer treatment, but its effectiveness can be significantly influenced by the patient’s microbiome. Recent studies have highlighted the intricate relationship between the gut microbiota …

Dec 18, 2024

Revolutionizing Cancer Treatment with CIK Cells

When it comes to modern medicine, advancements in cancer treatment and immune system rejuvenation are among the most exciting fields of study. One such breakthrough involves Cytokine-Induced Killer (CIK) cells. These spe…

Oct 7, 2024

Stem Cell Transplant: A Breakthrough in Medical Science

Stem cell transplant is a medical procedure that involves the transfer of stem cells from one person to another. This treatment is designed to replace damaged or diseased cells with healthy cells, leading to a new and im…

Feb 6, 2023

Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep

Biomedical engineering researchers developed a new cell classifier tool that takes a higher-resolution look at the life cycle of neuroepithelial stem cells, which led to the discovery and exploration of a new resting phase called Neural G0. This knowledge could help scientists to better understand glioma brain tumors and develop new methods of treatment.

Aug 2, 2021

Identification of Liver Cancer Stem Cell Stemness Markers Using a Comparative Analysis of Public Data Sets

National Institutes of Health and other agencies are funding high-throughput genomics and transcriptomics (‘omics) experiments that deposit digital samples of data into the public domain at a rapidly increasing scale. 1 , 2  The importance of these digital samples of data is further illustrated by the growing number of linked peer-reviewed publications that demonstrate its scientific value. 3 , 4  Investigations of cancer stem cells (CSC) is a promising research avenue, which leads to the generation of large volumes of unique data. There is growing evidence implicating CSCs in causing therapeutic resistance, tumor recurrence, and metastasis. It is known that these cells possess stem-like properties/functions and represent a critical subset within the tumor mass that is responsible for perpetuating the tumor, even in post-therapy patients. CSCs share similar properties with normal stem cells, including the ability to self-renew and differentiate that gives rise to heterogeneous cancer cells, making up the bulk of the tumor. 5

Jul 5, 2021

Engineered Natural Killer Cells Can Eliminate Glioblastoma Cancer Stem Cells

Deleting the TFG-β receptor in NK cells overcame immune suppression and enabled anti-tumor activity in preclinical models. Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity. Deleting the TFG-β receptor in NK cells, however, rendered them resistant to this immune suppression and enabled their anti-tumor activity.

Jun 19, 2021

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