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How stem cells synchronize to repair the spinal cord in axolotls

The spinal cord is an important component of our central nervous system: it connects the brain with the rest of the body and plays a crucial part in coordinating our sensations with our actions. Falls, violence, disease—various forms of trauma can cause irreversible damage to the spinal cord, leading to paralysis, sometimes even death.

Jun 20, 2021

Engineered Natural Killer Cells Can Eliminate Glioblastoma Cancer Stem Cells

Deleting the TFG-β receptor in NK cells overcame immune suppression and enabled anti-tumor activity in preclinical models. Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity. Deleting the TFG-β receptor in NK cells, however, rendered them resistant to this immune suppression and enabled their anti-tumor activity.

Jun 19, 2021

Recovering from a Stroke with MSCs Stem Cells

Stroke is an abrupt interruption of constant blood flow to the brain that causes loss of neurological function, there are 3 types:  a blocked artery ( ischemic   stroke ) or leaking or bursting of a blood vessel ( hemorrhagic   stroke ) and transient ischemic attack ( TIA also known as a mini stroke ). Different factors can lead to a stroke: high blood pressure, high cholesterol, diabetes, and those who smoke. Mesenchymal Stem Cells (MSCs) are not only safe but also one of the only treatment that can improve the patient condition following a stroke. Study show that with Cerebral artery occlusion model the efficacy of interferon‐γ–activated mesenchymal stem cells (aMSCγ) as an acute therapy for stroke.

Jun 2, 2021

3D-printing of human organs closer to reality

Researchers have designed a new bioink which allows small human-sized airways to be 3D-bioprinted with the help of patient cells for the first time. The 3D-printed constructs are biocompatible and support new blood vessel growth into the transplanted material. This is an important first step towards 3D-printing organs.

May 11, 2021

Muscle gene linked to type 2 diabetes

People with type 2 diabetes tend to have poorer muscle function than others. Now a research team has discovered that in type 2 diabetes, a specific gene is of great importance for the ability of muscle stem cells to create new mature muscle cells.

May 5, 2021

Pros and Cons of Using Various Stem Cells

Abundant somatic cells of donor can be used Issues of histocompatibility with donor/recipient transplants can be avoided Very useful for drug development and developmental studies

May 5, 2021

Repairing injured spinal cord using patients’ own stem cells

Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report Feb. 18 in the  Journal of Clinical Neurology and Neurosurgery .

May 5, 2021

MSCs Stem Cells with Severe COVID-19 ARDS

There is an ongoing critical need to improve therapeutic strategies for COVID-19 pneumonia, particularly in the most severely affected patients. Adult mesenchymal stem cell (MSC) infusions have the potential to benefit critically ill patients with acute respiratory syndrome SARS-COV-2 infection, but clinical data supporting efficacy are lacking.

May 5, 2021

What are Stem cells?

The word stem-cells is more and more used out of the medical circles, common people have hard time to understand or explain what are they, where do they come from. Why are they our best friend when it comes to medical rejuvenation: build a 3D organ or even help the human body to rebuild damaged tissues. Why stem cells are not more commonly used to cure or improve patients with critical diseases? What are the sources? How do I get stem cells treatments?

Apr 30, 2021

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