A 2026 meta-analysis of 15 RCTs shows MSCs cut acute GvHD incidence by 53% and chronic GvHD by 50%. A biomarker-guided trial identifies which transplant patients benefit most — and a cell-free exosome approach may be next.
Researchers have discovered that IL1 promotes the clonal expansion of TET2 knockout cells in blood, enhancing their self-renewal and myeloid bias, which is linked to an increased risk of leukemia and cardiovascular disease.
CD34 protein is a transmembrane glycoprotein that is expressed on the surface of hematopoietic stem and progenitor cells (HSPCs). This protein plays a significant role in the regulation of cell adhesion, migration, and differentiation. CD34 protein is a crucial biomarker that is widely used to isolate and purify HSPCs for...
Hematopoietic stem cell transplantation (HSCT) is a medical procedure that involves the transplantation of stem cells that are capable of forming blood cells. This advanced treatment option is used to treat various blood-related diseases such as leukemia, lymphoma, and multiple myeloma. HSCT has been found to be highly effective in...
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