Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep

Biomedical engineering researchers developed a new cell classifier tool that takes a higher-resolution look at the life cycle of neuroepithelial stem cells, which led to the discovery and exploration of a new resting phase called Neural G0. This knowledge could help scientists to better understand glioma brain tumors and develop...

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Identification of Liver Cancer Stem Cell Stemness Markers Using a Comparative Analysis of Public Data Sets

National Institutes of Health and other agencies are funding high-throughput genomics and transcriptomics (‘omics) experiments that deposit digital samples of data into the public domain at a rapidly increasing scale.1,2 The importance of these digital samples of data is further illustrated by the growing number of linked peer-reviewed publications that demonstrate...

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Engineered Natural Killer Cells Can Eliminate Glioblastoma Cancer Stem Cells

Deleting the TFG-β receptor in NK cells overcame immune suppression and enabled anti-tumor activity in preclinical models. Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by...

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