Deleting the TFG-β receptor in NK cells overcame immune suppression and enabled anti-tumor activity in preclinical models. Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by...
Stroke is an abrupt interruption of constant blood flow to the brain that causes loss of neurological function, there are 3 types: a blocked artery (ischemic stroke) or leaking or bursting of a blood vessel (hemorrhagic stroke) and transient ischemic attack (TIA also known as a mini stroke ). Different factors can lead to a...
Researchers have designed a new bioink which allows small human-sized airways to be 3D-bioprinted with the help of patient cells for the first time. The 3D-printed constructs are biocompatible and support new blood vessel growth into the transplanted material. This is an important first step towards 3D-printing organs. (more…)
People with type 2 diabetes tend to have poorer muscle function than others. Now a research team has discovered that in type 2 diabetes, a specific gene is of great importance for the ability of muscle stem cells to create new mature muscle cells. (more…)
In view of data scarcity to guide decision-making in breastfeeding women, we evaluated how mRNA vaccines impact immune response of lactating health care workers (HCW) and the effector profile of breast milk transferred immune protection. (more…)
Researchers have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice. The drug works by reinvigorating a cellular cleaning mechanism that gets rid of unwanted proteins by digesting and recycling them. (more…)
Abundant somatic cells of donor can be usedIssues of histocompatibility with donor/recipient transplants can be avoidedVery useful for drug development and developmental studies (more…)
Intravenous injection of bone marrow derived stem cells (MSCs) in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report Feb. 18 in the Journal of Clinical Neurology and Neurosurgery. (more…)
There is an ongoing critical need to improve therapeutic strategies for COVID-19 pneumonia, particularly in the most severely affected patients. Adult mesenchymal stem cell (MSC) infusions have the potential to benefit critically ill patients with acute respiratory syndrome SARS-COV-2 infection, but clinical data supporting efficacy are lacking. (more…)
The word stem-cells is more and more used out of the medical circles, common people have hard time to understand or explain what are they, where do they come from. Why are they our best friend when it comes to medical rejuvenation: build a 3D organ or even help the...
